Noopept Reviews – Is This a Powerful Brain Enhancing Supplement?

Noopept is an all-natural nootropic supplement or powder which aims to boost cognitive functions like memory, learning, mental focus, and mood.
Advertising Disclosure: The Performance Insiders is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more.


The brain is one of our most important organs, and staying mentally well and sharp is essential to every aspect of our lives. According to medical research following a healthy lifestyle can do a lot to boost your brain health, however, you may also consider adding a natural nootropic supplement to your day.

Noopept is one of the many options on the market which may have an impact. In this review, we’ll look at the details and give you our honest option of the product and its value.

What is Noopept?

Noopept is a nootropic available in powder or supplement form which contains n-phenylacetyl-l-prolylglycine ethyl ester as the sole ingredient. While we have focused on the Nootropics Depot brand, this formulation is available from other manufacturers and brands.

This bioactive substance promises to improve cognitive functions like memory, attention, and learning as well as boost mood and decrease anxiety levels. There’s some research supporting its benefits, but the Noopept review feedback for this product was only moderately positive.


Editor’s Rating
3.8 / 5.0
Overall Rating


Noopept is an all-natural product which promises to boost mood, decrease anxiety, and improve cognitive functions like memory and focus.

You can purchase Noopept on the official Nootropics Depot site:

  • 90 Count Jar, 10 mg – $19.99
  • 90 Count Jar, 30 mg – $24.99
  • Powder, 10g Jar – $24.99

Shop On AmazonShop On Walmart*All the prices mentioned on their websites are subject to change.

  • 3.7/ 5


  • 3.2/ 5

    Value For Cost

  • 3.9/ 5


  • 3.7/ 5


How We Tested Noopept?

Certainly! Here’s an article that details our team’s evaluation of Noopept, a supplement known for its cognitive enhancement properties. A comprehensive 30-day trial was conducted, during which participants were administered Noopept, and their progress was meticulously tracked.

The article provides extensive information about the ingredients contained in Noopept, emphasizing their advantages and mechanisms of action. The trial results demonstrated a significant improvement in cognitive function among the participants.

Based on the findings, the article concludes that Noopept is a safe and effective supplement for individuals seeking to enhance their mental performance and overall cognitive abilities.


Manufacture Nootropics Depot.
Made In Arizona, 85284, United States.
Type Memory supplement.
Serving Size Take 2 Capsules Daily.
Eve 90 Capsules.
Main Benefits Improved focus and concentration, Increased creativity, Enhanced memory, and learning.
Key Ingredient N-Phenylacetyl-L-Prolylglycine Ethyl Ester.
Allergen Warning Not Available.
Safety Information Pregnant or breastfeeding women are generally advised to avoid using Alpha Brain.
  • 90 Count Jar, 10 mg – $19.99
  • 90 Count Jar, 30 mg – $24.99
  • Powder, 10g Jar – $24.99

About the Brand

During the 1990s, Nootropics Depot, an Arizona company, developed Noopept, a synthetic nootropic compound. Noopept belongs to the Racetam class of nootropics and has gained popularity in Eastern Europe, where it is prescribed for various cognitive impairment issues resulting from brain trauma and degenerative diseases like Alzheimer’s. While Noopept has demonstrated effectiveness as a therapeutic solution, it is primarily renowned for its potent cognitive-enhancing effects.

While Noopept is categorized as a Racetam, NCBI research suggests that it is approximately 1,000 times more potent than the original nootropic, Piracetam. This indicates that Noopept can produce significant effects even at low doses, setting it apart from many other nootropics. Noopept is available in capsule form or as a soluble powder.


” Noopept Image/CognitiveHealthDigest.

What is the Key Ingredient and How Does It Work?

The primary active ingredient in Noopept is n-phenylacetyl-l-prolylglycine ethyl ester, which is a synthetic substance made by a pharmaceutical company in Russia. Based on a similar nootropic, piracetam, this compound promises great cognitive benefits.

A study published in ActaNaturae by Y. V. Vakhitova, et al examined the underlying mechanism for n-phenylacetyl-l-prolylglycine ethyl ester and concluded that its structure supports its neurotropic benefits [1].

The formula likely works through several mechanisms. It could prevent calcium and glutamate toxicity by keeping levels in balance. A study published in the Journal of Biomedical Science by Rita U Ostrovskaya and Yulia V Vakhitova, et al found that the compound reduced oxidative stress and calcium overload [2].

In addition, it may boost levels of the hormone BDNF, which supports neural cell health, improves cell transmission, and helps develop new neural networks.

A study in the Bulletin of Experimental Biology and Medicine by R U Ostrovskaya, et al concluded that n-phenylacetyl-l-prolylglycine ethyl ester stimulates levels of neurotropic factors NGF and BDNF in the brain hippocampus of rats [3].

Noopept could also increase levels of key brain neurotransmitters involved in cognitive functioning and mood. As we said in our review of Youthful Brain, this could improve memory, learning, mental focus, and other functions. It may also help slow the progress of cognitive decline.

A study published in the Journal of Psychopharmacology by Rita U Ostrovskaya and Marina A Gruden, et al on an Alzheimer’s disease model found that n-phenylacetyl-l-prolylglycine ethyl ester restored spatial memory and enhanced immunoreactivity [4].

Noopept has powerful anti-inflammatory agents which decrease swelling in the brain stem for improved overall neural health. It’s also high in antioxidants which lower oxidative stress by abolishing free radicals.


This formula decreases excess calcium and glutamate to prevent toxicity, increases levels of BDNF, and it has powerful antioxidant and anti-inflammatory agents which reduce swelling and repair damage to brain cells.

Similar Product

Product Rating Review
Mind Lab Pro Mind Lab Pro Review
Nootrobox Nootrobox Review
Cognium Cognium Reviews
Rejuva Brain Rejuva Brain Reviews
Cognifocus Cognifocus Review

What are the Noopept benefits?

Noopept is a popular nootropic compound that is known for its cognitive-enhancing properties. While individual experiences may vary, some potential benefits of Noopept include:

  • Improved cognitive function: It has been suggested that Noopept improves memory and learning. It might aid in information consolidation and retrieval, enhancing memory and overall cognitive performance.
  • Reduced anxiety and depression: Noopept may be helpful for patients with anxiety or depression because medical research indicates it has anxiolytic and antidepressant properties.
  • Neuroprotective benefits: Noopept has been demonstrated to possess neuroprotective qualities, suggesting that it might aid in defending the brain against harm from toxins or injury.
  • Increased motivation and productivity: Noopept has been reported to improve motivation and productivity, allowing users to get more done in a shorter period of time.

Our Research and Rating

Here is our score, based on scientific evidence, of how likely Noopept will be effective for its claimed benefits:

  • Enhances Memory *3.8/5
  • Sharpens Mental Focus*3.7/5
  • Decreases Stress and Anxiety *3.9/5
  • Improves Mood *3.7/5

We used the insights from our research and testing to assign a star rating from one to five (five being the best; one being the worst) to this product.

Pros and Cons of Noopept


  • This supplement may improve your memory.
  • Noopept could enhance mental focus and concentration.
  • This product might decrease stress and anxiety.
  • Noopept supplement could have neuroprotective benefits.
  • The product may improve your mood.


  • Noopept relies on only one primary active ingredient.
  • The capsules contain artificial coloring.
  • The return policy is only for sealed bottles.

Product Comparison

To help you decide, here is a brief comparison of our top picks:

Table of Content Brain Bright Noocube Noopept
Image Brain Bright Noocube Noopept
Rating 2.7 / 5.0 4.9 / 5.0 3.8 / 5.0
Price $37.77 $64.99 $19.99
Sold By BioTrust Wolfson Brands Nootropics Depot
Age Range Adult Adult Adult
Brand Name BioTrust Wolfson Brands Nootropics Depot
Dosage 2 Capsule 1 Capsule 2 Capsule
Ingredients Riboflavin Resveratrol N-Phenylacetyl-L-Prolylglycine Ethyl Ester
Unit Count 60 Capsule 60 Capsule 90 Capsule
Where To Find Find out more Find out more Find out more

Frequently Asked Questions

  • Q. Where Can You Buy Noopept?

  • Q. How Do You Take Noopept?

  • Q. What is the Return Policy or Guarantee?

  • Q. What Sets It Apart From the Competition?

  • Q.Is Noopept Safe?

  • Q.What are the risks of Noopept?

What Do the Noopept Reviews Say?

There are a number of Noopept review postings online, and they vary in their opinions of the product. There are a number of people who said it worked very well to boost their cognitive functioning, while others said it didn’t do much for them. These are a few of the user comments:

Noopept Works

This has been my favorite. Noticed a difference after a couple of weeks of use. It will “kill your buzz” quick if you are a drinker after taking it for a week.
Ryan, Nootropics Depot Site

I Don’t Doubt the Ingredients

I just don’t believe the hype after trying this for a few weeks. Seems to have done nothing except for headaches. Read about this and really figure out if you want to experiment with yourself.
Joshua, Amazon Customer

Seems to Work!

I tried a wide range of nootropics and life extension supplements, and this particular substance has probably had the most directly observable positive effect.
Max V, Amazon Customer


Noopept is an organic supplement or powder containing one brain-boosting ingredient, n-phenylacetyl-l-prolylglycine ethyl ester. It promises to improve cognitive health, boost memory, sharpen mental focus, enhance mood, decrease stress, and slow cognitive decline. It’s a reasonably-priced product which has some scientific support.

The Noopept review postings online varied quite a bit in terms of customer experience. While some said it was an amazing new smart drug, others found the Noopept benefits quite limited. Some users said they would keep taking it, while others mentioned that they would move on to other products.

Noopept by Nootropics Depot is a safety manufactured supplement made in an FDA registered facility in the USA. However, there’s a chance that you may experience mild side effects like dizziness or nausea. If the symptoms are severe, stop taking the product. Prior to taking any new supplement you should see a doctor and get medical approval.

More than ever people of all ages are struggling with memory problems. People are unable to disconnect from their work, while students are under immense pressure to perform. Brains are overloaded with information that must be remembered. A quality memory enhancement product should contain clinically proven ingredients that will help to enhance not only memory, but also focus and night concentration. Memory products should help to optimize overall mental health and brain function. Most importantly a memory product should work safely and gently to promote cognitive function.

Below you'll find some of the most effective memory products on the market today, in our opinion.

Rating Table

Our Top Memory Supplements Choices



Noocube Overall rating 4.9/5 Overall rating Read Full Review
  • Support Brain HealthSupport Brain Health
  • Improve Focus & ConcentrationImprove Focus & Concentration
  • Safe & EffectiveSafe & Effective
  • Money-Back GuaranteeMoney-Back Guarantee
  • Quality of IngredientsQuality of Ingredients


  • Gain a Laser-Like Focus.
  • Hone Your Problem-Solving Techniques.
  • Increasing Memory and Mental Clarity.
  • Reduce Brain Fog Brought by By Weariness.


  • NooCube is only available through the manufacturers website.
  • Expensive and difficult to buy
Bottom Line

Noocube is a reputed dietary supplement and a well-tested nootropic made with all-natural ingredients. It boosts brain functions like memory and slows down neurodegeneration and brain aging. Such properties make it a perfect supplement for prolonged use.

Check Price

Alpha Brain

Alpha Brain Overall rating 4.8/5 Overall rating Check Price
  • Support Brain HealthSupport Brain Health
  • Improve Focus & ConcentrationImprove Focus & Concentration
  • Safe & EffectiveSafe & Effective
  • Money-Back GuaranteeMoney-Back Guarantee
  • Quality of IngredientsQuality of Ingredients


  • Ideal for both men and women to enhance their focus and cognitive speed.
  • Helps support memory, mental speed and focus to promote lasting mental clarity.
  • Formulated with high-quality nutrients to help support focus.
  • Help reduce memory fog.


  • Greater cost.
  • Side effects include nausea and vomiting.
Bottom Line

Onnit Alpha Brain Collection is a set of supplements developed using the thinking and focus formula. This collection includes dietary supplements as capsules in addition to Alpha Brain Instant formulations and focus shots.

Check Price


Nootrogen Overall rating 4.7/5 Overall rating Check Price
  • Support Brain HealthSupport Brain Health
  • Improve Focus & ConcentrationImprove Focus & Concentration
  • Safe & EffectiveSafe & Effective
  • Money-Back GuaranteeMoney-Back Guarantee
  • Quality of IngredientsQuality of Ingredients


  • The formula supports cognition and focus.
  • The brain supplement helps reduce stress and anxiety, enabling you to remain calm.
  • It helps increase productivity and learning performance.
  • Nootrogen helps improve memory and the ability to concentrate.


  • The only place to get Nootrogen is online at the official website.
  • Individual results may vary depending on a variety of physical factors.
Bottom Line

Nootrogen is a dietary nootropic supplement to boost brain function, memory, concentration, focus, and energy. The nutrient booster formula supports cognitive function without causing side effects.

Check Price


BrainPill Overall rating 4.7/5 Overall rating Check Price
  • Support Brain HealthSupport Brain Health
  • Improve Focus & ConcentrationImprove Focus & Concentration
  • Safe & EffectiveSafe & Effective
  • Money-Back GuaranteeMoney-Back Guarantee
  • Quality of IngredientsQuality of Ingredients


  • Scientifically-backed ingredients.
  • Discounts with larger orders.
  • 60-day money-back guarantee.
  • Antioxidants support a healthy brain long-term.


  • Free shipping only on larger orders.
  • Some ingredients lack strong evidence for their effects.
Bottom Line

Brain Pill is a widely popular supplement that boosts mental health and cognitive abilities. It is formulated with some effective natural ingredients which improved your focus by enhancing blood circulation in the brain cells. It not only improves your mental alertness but also reduce declines in brain function.

Check Price

PrimeGENIX CortiSync

PrimeGENIX CortiSync Overall rating 4.7/5 Overall rating Check Price
  • Support Brain HealthSupport Brain Health
  • Improve Focus & ConcentrationImprove Focus & Concentration
  • Safe & EffectiveSafe & Effective
  • Money-Back GuaranteeMoney-Back Guarantee
  • Quality of IngredientsQuality of Ingredients


  • Begins balancing cortisol in 2 weeks.
  • Boost strength and energy and strength.
  • Improve the body's working.
  • Reduce hunger.
  • Improve brain health and metabolism.


  • This is a popular item that could sometimes run out of stock.
  • One can only buy it online, not in stores.
Bottom Line

Cortisync is a dietary supplement made from natural ingredients that is meant to lower cortisol levels. It uses a combination of adaptogens that stop your body from reacting to stress and lower cortisol levels.

Check Price

Brain C-13

Brain C-13 Overall rating 4.7/5 Overall rating Check Price
  • Support Brain HealthSupport Brain Health
  • Improve Focus & ConcentrationImprove Focus & Concentration
  • Safe & EffectiveSafe & Effective
  • Money-Back GuaranteeMoney-Back Guarantee
  • Quality of IngredientsQuality of Ingredients


  • It helps you stay sharp and focus.
  • It improves your memory recall.
  • It improves circulation and increases the flow of oxygen.
  • It helps in improving your cognitive health.
  • It plays a role in quick thinking


  • You cannot use the supplement if you are under the age of 18.
  • Pregnant women cannot use the supplement.
  • The official website does not have any information about the side effects of the supplement
Bottom Line

Brain C-13 is a unique supplement by Zenith Labs that improves brain health and shields the brain from harmful chemical compositions by drastically improving your memory and keeping your mind razor-sharp.

Check Price

**This is a subjective assessment based on the strength of the available informations and our estimation of efficacy.

*Result may vary. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. The information contained in this website is provided for general informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not be relied upon as a medical advice. Always consult your doctor before using any supplements.

*Disclosure of Material connection: Some of the links in the post above are "associate sales links." This means if you can click on the link and purchase an item, we will receive a commission. Regardless, we only recommend products or services which we use personally and/or believe will add value to our readers. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: “Guides Concerning the Use of Endorsements and Testimonials.”


Our mission at Cognitive Health Digest is to improve quality of life. In everything we do, it is our objective to provide up-to-date information. We have a team of copywriter, editor, and author with tons of experience.

Customer Reviews for Noopept

Noopept Reviews – Is This a Powerful Brain Enhancing Supplement?
3.8 / 5.0
Overall Rating
Review this Product
Write a Review
Review Guidelines

Hints on how to write a helpful review

A great review should have the following qualities:

  • A helpful review should connect and engage with the readers using personal experience.
  • An excellent review provides the readers with cogent and unbiased information necessary to help them make the best choice.
  • A review must be well-formatted to make reading easier by using multiple paragraphs and avoiding caps.
  • The primary goal of your review must remain to provide accurate and non-salesy information.
  • Above all, let your review be fair and honest.

We have high level of professional editorial section with zero tolerance policy on fake reviews.

To maintain the genuineness of our brand, we ensure all customer reviews submitted to us are verified and confirmed before publishing. Though we might not be a 100% accurate, however, we try our best to ensure being next to best. For a thorough verification of submitted reviews, we spend close to 7 working days before allowing any customer review to be published since we also work on the earliest submissions first.


How to Upload your Proof of Purchase:

Please follow the instructions listed below to upload your electronic proof of purchase.

  • To upload your physical paper receipt, simply take a picture of it with your camera or phone. You may also try taking a still picture of it with your computer’s webcam.
  • Once you have taken the picture, save the image as a JPG, TIF, or PDF file.
  • Please note that you cannot upload a file that is larger than 2MB.
  • Then all you have to do is click the Browse button and search for your receipt picture file. You can also drag and drop the file into the provided field.

If you are still not able to upload your proof of purchase, please contact us for further assistance (take a moment to look over the sample bill below).


Your email address will not be published.

Your Rating:05

Privacy Policy
Submitting this review means that you agree to our Review Guidelines, confirming that you are a verified customer who has purchased the product and may have used the merchandise or experienced the service, and providing only a real interaction and experience without ulterior motives or has an affiliate or business with the company in any way. By ticking this box and submitting this review, you also accept that submitting fake reviews is a violation of Cognitive Health Digest Terms of Use and such conduct will not be tolerated.

Thanks for submitting your comment!

This Cognitive Health Digest content has been reviewed, as well as checked for facts, so as to guarantee the best possible accuracy.

We follow a strict editorial policy, especially related to the sources we use. Our articles are resourced from reputable online pages, with research drawn from academic institutions and peer-reviewed studies. You can click on the numbers in the parentheses (1, 2, etc.) and check out those references.

The feedback form on this page can be used to report content that is not accurate, up-to-date or questionable in any manner.

We do NOT intend for the information presented through our articles to replace the medical relationship with a qualified physician, nor does it represent specialized advice.


Advertising Disclosure

The content that appears on this page is presented as an overview vs. comparative marketing. The provided information includes product information, overviews, buying guides, and product specifications. All trademarks, registered trademarks and service-marks mentioned on this site are the property of their respective owners. If something is factually inaccurate please contact us and let us know. By contributing your product facts helps to better serve our readers and the accuracy of the content.

The table below does not include all companies or all available products in the market but those that we promote as their affiliates. In full compliance with the FTC guidelines, please assume that any and all links on the table are affiliate links, and we may receive compensation if you click one of these and make a purchase. We are independently owned and the opinions expressed here are our own. All editorial content is written without prejudice or bias, regardless of sponsor or affiliate associations.